New Jersey Toenail Clippings to Be Collected for Toxic Testing

From ABC News:

Toenail clippings could be the key to discovering if thousands of residents of Garfield, N.J., have been exposed to a toxin spill 30 years ago that could cause cancer.

"Toenails grow slower than fingernails or than hair so you can track or detect chronic exposure in toenails," Judith Zelikoff a professor and research scientist at New York University's School of Medicine, told ABCNews.com.

One millimeter of toenail can reveal information up to 18 months of exposure.

The risk of contamination comes from a 1983 leak where thousands of pounds of hexavalent chromium seeped out of a tank at a factory surrounded by houses and apartment buildings.

Scientists say only 30 percent of the leak was cleaned up, and 10 years later chromium was found in area basements and a firehouse.

The underground plume is about three-quarters of a mile wide and a little less than a mile long, according to the Environmental Protection Agency. The "area of concern" covers more than 600 homes and businesses with the potential of more than 3,700 people being possibly effected, Zelikoff said.

Residents of the area are being given kits that include a stainless steel nail clipper (cheap nail clippers may contain traces of chromium), a plastic bag for the clippings, nail polish remover, alcohol swabs, instructions and an envelope for the clippings. The results will take about five weeks.

Posted: 3/26/2013 3:39:00 PM

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Hip Joints Set Off New Rush to Court

From The Wall Street Journal:

About 1,000 lawsuits have been filed in federal and state courts accusing the drug and medical-device maker of knowing about problems with some of its metal-on-metal hip joints before Johnson & Johnson's DePuy Orthopaedics Inc. unit stopped making them in 2009. J&J, which later recalled the joints world-wide, denies the allegations and is fighting back.

J&J recalled its metal-on-metal hip joints last year after British data showed them wearing down or otherwise requiring replacement at unusually high rates. That was the first indication the company had of any flaws in the product, the DePuy spokeswoman said.

Some patients had to undergo risky and expensive surgery to remove and replace the recalled implant—a metal ball and socket designed to replicate a natural hip joint.

J&J estimates that about 37,000 patients in the U.S. and about 93,000 world-wide have received the recalled device. The DePuy spokeswoman said the company will cover the cost of all medical care associated with the device, including replacement surgery.

Some patients who received the recalled hip joint, the so-called articular surface replacement, or ASR, system, say in their lawsuits that medical tests showed chromium and cobalt in their bloodstreams and allege the potentially toxic metals came from parts of the joint wearing down and leaching into their system.

Though the DePuy spokeswoman said the recalled joints contain cobalt and chromium, she said it wasn't clear whether the devices contributed to elevated levels of those metals in patients' blood or how many patients might have this problem.

In May, the FDA said particles from the metal-on-metal hip joints, such as cobalt and chromium, might wear off and make their way into a patient's blood. The agency said this could contribute to heavy concentrations of cobalt and chromium in the body but it wasn't clear if that would cause symptoms—such as trouble seeing and diseased heart muscle—that had been reported by a "small number" of those who received the joints. To better understand potential health effects, the FDA ordered J&J and other makers of the metal-on-metal joints to monitor the devices for possible health risks.

Posted: 8/2/2011 3:41:00 PM

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DePuy Hip Metal Poisoning May Develop Without Hip Pain or Other Symptoms

From eMailWire:

Patients who have been implanted with the recalled ASR systems may be at risk for DePuy metal poisoning due to the metal-on-metal design of the system. As the components rub against each other, they can release cobalt and chromium into the body. Some individuals may develop an inflammatory reaction to these metal particles, causing fluid build-up in the joint and its surrounding tissue. Initially, DePuy hip metal poisoning may be painless; however, left untreated, it can damage the muscles, bones and nerves around the hip.

Posted: 2/8/2011 9:37:00 AM

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EPA Finds Elevated Arsenic Levels in Water Near Coal Ash Spill

From the Associated Press:

The Environmental Protection Agency has released data showing levels of arsenic more than 100 times safe levels in the water after a coal ash spill that flooded an East Tennessee neighborhood.

The EPA has said that sediment and water samples from near the spill were above federal maximum levels for contaminants. The data released Friday showed total arsenic levels in one water sample was 149 times the maximum level.

And from The New York Times:

An environmental advocacy group’s tests of river water and ash near the site of a huge coal ash spill in East Tennessee showed levels of arsenic, lead, chromium and other metals at 2 to 300 times higher than drinking water standards, the group said Thursday.

The findings far exceed levels reported by the Tennessee Valley Authority, the Environmental Protection Agency or the Tennessee Department of Environment and Conservation. Those agencies have reported elevated levels of thallium, lead and arsenic found near the spill but have not released the full results of those tests.

The T.V.A. and the state have released only the results of tests on water sampled from the Tennessee River just after the spill at a spot six miles away and upstream of the ash flow, which showed that the water at that spot met drinking standards.

The ash spill occurred Dec. 22 when an earthen dike at the Kingston Fossil Plant, a T.V.A. coal utility, gave way, spreading a billion gallons of wet coal ash, known to contain heavy metals, across about 300 acres and into tributaries of the Tennessee River.

The independent test results were released by Appalachian Voices, an environmental advocacy group based in Boone, N.C. The tests were conducted using standard E.P.A. methods, said Dr. Shea Tuberty, an environmental toxicologist at Appalachian State University who helped analyze the results.

Paul E. Davis, the director of water pollution control for the Tennessee environmental department, said he would have his staff compare the results of the tests with other sample results. “If the work that Appalachian State has done indicates that there’s been a violation, we’re very interested,” Mr. Davis said.

Appalachian Voices sampled water from three locations — near the spill site, about half a mile downstream and about two miles downstream — and found eight metals that exceeded drinking water limits. At the two-mile point, arsenic was at a level 35 times the drinking water limit. The group also expressed concern that standards for fish and aquatic life, which are stricter than drinking water standards, in part because heavy metals accumulate in animal tissue over time, had been exceeded.

“These are some of the most astonishing water-quality sampling results I’ve ever seen in my 10 years of working on rivers,” said Donna Lisenby, a spokeswoman for Appalachian Voices who helped collect the samples.

A news release from the group included a statement by Robert F. Kennedy Jr., chairman of the national Waterkeeper Alliance, who said, “Although these results are preliminary, we want to release them because of the public health concern and because we believe the T.V.A. and E.P.A. aren’t being candid.”

Jim Allen, a spokesman for the power authority, said, “T.V.A. has every confidence in the integrity of its sampling methodologies as well as those of the Tennessee Department of Environment and Conservation and the Environmental Protection Agency. T.V.A. also is obtaining independent sampling.”

Mr. Allen said he could not say why the agency had not released the full results of the samples that had been tested thus far.

Laura Niles, a spokeswoman for the E.P.A., said she was waiting for results to release to the public. “I’m getting that question daily, believe me,” Ms. Niles said.

Posted: 1/2/2009 1:36:00 PM

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Presence of migrated heavy metals was found in pacifier samples

From The Telegraph (Calcutta, India):

The Consumer Education and Research Society (CERS), Ahmedabad, tested a range of pacifiers, teethers and nipples for the presence of migrated heavy metals (lead, cadmium and chromium), considering their high toxicity. The findings are so alarming that CERS published the report without testing larger sample sizes.

Scientists and experts are of the opinion that the presence of metals like lead, cadmium and chromium, even in the smallest amount, is hazardous to health. Even the faintest trace of these metals in pacifiers, teethers and nipples, meant for sucking and biting, can pose a health risk to infants.

The lead content in toys has become a global issue. But there are no separate standards for infant toys like pacifiers, nipples and teethers.

Infant toys cannot be clubbed with children’s toys. These toys are meant for sucking and biting over a period of time, owing to which the toxic elements easily leak out with the saliva and get ingested into the body. 

A total of eight samples of pacifiers, teethers and nipples were tested for migrated elemental lead (Pb), calcium (Cd) and chromium (Cr). The results revealed that none of the toy samples was free from lead. The migrated lead content varied from 2.7 to 9.6 ppm (parts per million). Although this figure complies with the standards set by the BIS (Bureau of Indian Standards), the presence of lead is not acceptable, particularly in infant toys.

Nuby Natural Flex Pacifier contained 5.5 ppm of lead and Disney Baby Soother and Holder Set had 5.6 ppm of lead. Out of the three teethers tested, Mom’s and Me water-filled teether had the highest lead content (9.6 ppm), while Fisher Price Penguin water-filled teether had the lowest amount of lead (5.4 ppm). The Yash Yellow rubber nipple had the highest lead content (4.8 ppm) and Piyu silicon rubber nipple had the lowest (2.7 ppm). This is dangerous because the chewing and swallowing of toys by infants make them more vulnerable to toxic lead.

Cadmium, a heavy metal used as stabilisers in plastic and paints, was found in all the samples tested. The samples contained cadmium in a range of 0.1 to 0.6 ppm. In the pacifiers tested, the Nuby brand had more cadmium (0.6 ppm) than Disney (0.1 ppm). Mom’s and Me had more cadmium (0.3ppm) than Lucky and Fisher Price. Both these brands had 0.2 ppm of cadmium. Yash Yellow had the lowest amount of cadmium (0.1 ppm) while Alfa silicon rubber nipple had the maximum (0.4 ppm).

Cadmium is a nephrotoxin which can damage the kidneys. Ingestion of cadmium may cause abdominal pain, nausea and even death. Even a small quantity of cadmium may pose a great danger to an infant’s body.

Traces of chromium were found in all the samples tested. The amount of migrated chromium varied from 0.4 to 5.0 ppm. The Nuby Natural Flex Pacifier had a chromium content of 2.8 ppm. Out of the three teethers tested Mom’s and Me water-filled teether contained the highest amount of chromium (5.0 ppm). Alfa silicon rubber nipple contained 4.4 ppm of chromium while Yash Yellow rubber nipple contained the least (1.0 ppm).

Like lead and cadmium, chromium is also considered toxic. Highly toxic Cr (VI) may cause irritation and asthma attacks. Young people may be more susceptible to toxic effects of chromium than adults.

Commenting on the test results, Mattel Inc. said it does not use lead or cadmium compound as stabilisers for plastics or PVC. The minute amount of lead detected may have resulted from exposure to dust, equipment or even water. The mere detection of lead at these levels, which are below the regulatory standards, doesn’t equate to a health risk.

CERS stresses that the test samples were completely sealed, having no room for dust. The laboratory uses good quality triple distilled water, which has almost zero lead content. Hence the lead content measured in the test sample of Fisher Price Penguin water teether was from the sample only.

Posted: 7/28/2008 4:12:00 PM

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